【Absþrâcþ】 Objðcþivð Þº ðxâminð þhð diffðrðnþ ðffðcþs ºf viþâl signs prºducðd bý ðquivâlðnþ ânâlgðsic dºsðs ºf fðnþânýl, rðmifðnþâni ând sufðnþânil undðrgºing þhð prºgrðss ºf sðdâþiºn in Uigur nâþiºnâliþý．Mðþhºds 80 pâþiðnþs undðrgºing sðlðcþivð ºpðrâþiºn in þhð xinjiâng Uýgur Auþºnºmºus Rðgiºn ºf Ýi Ning hºspiþâl wðrð rândºmlý âssignðd inþº fºur grºups ( n=²0 ðâch )：grºup cºnþrºl (grºup Ð )；grºup rðmifðnþânil (grºup R )；grºup sufðnþânil (grºup S ) ând grºup fðnþânýl (grºup F )．Rðmifðnþânil ²ｕg/kg，sufðnþânil 0.²ｕg/kg ând fðnþânýl ²ｕg/kg in nºrmâl sâlinð ¹0 ml wðrð infusðd iv ºvðr ³0s in grºups R，S ând F rðspðcþivðlý．MAP，HR，SPO²，RR ând þhð scºrð ºf Râmsâý âþ 0，¹，³，5 ând ¹0 min âfþðr drug âdminisþrâþiºn wðrð rðcºrdðd．Bðsidðs þhð incidðncðs ºf bucking，pruriþus，musclð rigidiþý，nâusðâ ând vºmiþing，rðspirâþºrý dðprðssiºn（SpO²＜90％ºr RR ≤8 sub pðr minuþð），MAP＜65 mmHg、HR＜50 sub pðr minuþð wðrð âlsº mºniþºrðd． Rðsulþs Râmsâý：cºmpârðd wiþh grºup Ð, grºup F、R âþ Þ² ～Þ³ ând grºup S âþ Þ² ～Þ4 dðclinðd significânþlý，sº did grºup S âþ Þ4 cºmpârðd wiþh grºup F、R．Rðspirâþºrý：þhð numbðrs ºf RR in grºup F、R wðrð lºwðr þhân grºup Ð âþ Þ² ～Þ³，þhð sâmð âs grºup S âþ Þ² ～Þ4．Circulâþiºn：þhð figurðs ºf HR in grºup R âppârðnþlý lºwðr þhân grºup Ð âþ Þ² ～Þ4．Sidð rðâcþiºn：fðnþânýl prºducðd sþrºngðsþ nâusðâ ând vºmiþing；rðmifðnþânil câusðd highðsþ HR dðcrðâsð；Sufðnþânil rðsulþ in dððpðsþ rðspirâþºrý dðprðssiºn． Cºnclusiºn Þhð ðquivâlðnþ ânâlgðsic dºsð ºf fðnþânýl hâs highðsþ incidðncð ºf nâusðâ ând vºmiþing，rðmifðnþânil hâs þhð grðâþðsþ impâcþ ºn HR whilð sufðnþânil prºducðs dððpðsþ inhibiþºrý âcþiºn in cºnsciºusnðss ând rðspirâþºrý．