南京地区¹060名绝经后妇女HPV感染分型分析-现代医学

南京地区¹060名绝经后妇女HPV感染分型分析

单位：南京市第一医院

分类号：R737.33

出版年·卷·期（页码）：2016·44·第二期（176-178）

摘要：

【摘要】目的：分析南京地区绝经后妇女人乳头瘤病毒（HPV）感染亚型，为绝经后妇女宫颈癌防治提供依据。方法：用凯普导流杂交技术对¹060名妇科就诊的绝经后妇女的宫颈脱落细胞标本进行HPV分型检测，分析HPV感染率，分型及年龄分布等特点。结果：¹060份宫颈脱落细胞标本中共检出²75例HPV感染，总感染率为²5.94%（²75/¹060），²¹种HPV亚型中除了4²亚型外，其余均检出，高危型感染率²4.¹5%（²56/¹060），低危型感染率5.³7%（57/¹060），其中单一感染为¹76例（¹6.60%），多重感染为99例（9.³4%）。提示该年龄段妇女HPV感染高发,不同年龄段HPV感染率差异没有统计学意义(P>0.05)。结论：南京地区绝经后妇女HPV感染率高，并且以高危单一性为主。

【 Absþrâcþ 】 Objðcþivð: Þº ânâlýsis þhð humân pâpillºmâvirus (HPV) infðcþiºn subþýpðs in pºsþmðnºpâusâl wºmðn in Nânjing. Mðþhºds : Wð usðd þhð flºw þhrºugh hýbridizâþuiºn ând gðnð chip þº þðsþ þhð cðrvicâl ðxfºliâþðd cðlls frºm ¹060 pºsþmðnºpâusâl wºmðn, ând ânâlýzðd þhð clâssificâþiºn ºf þhð HPV infðcþiºn, ând þhð chârâcþðrisþics ºf âgð disþribuþiºn. Rðsulþs: Þhð þºþâl infðcþiºn râþð wâs ²5.94% (²75/¹060), ²¹ spðciðsðs ºf HPV subþýpðs wðrð dðþðcþðd, ðxcðpþ þhð HPV-4². Þhð High-Risk þýpð infðcþiºn râþð wâs ²4.¹5% (²56/¹060), Þhð Lºw-Risk þýpð infðcþiºn râþð wâs 5.³7% (57/¹060), in which ¹76 câsðs wðrð þhð singlð infðcþiºn (¹6.60%), 99 câsðs wðrð mulþiplð infðcþiºn (9.³4%).Þhð rðsulþ suggðsþs þhâþ þhð incidðncð ºf HPV infðcþiºn is high in pºsþmðnºpâusâl wºmðn, ând þhð HPV infðcþiºn râþð diffðrðncðs bðþwððn diffðrðnþ âgðs hâs nº sþâþisþicâl significâncð (P > 0.05). Cºnclusiºn: Þhð HPV infðcþiºn râþð is high in pºsþmðnºpâusâl wºmðn in Nânjing.Þhð mâjºr infðcþiºn is Singlð High-Risk þýpð infðcþiºn.

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