高危型人乳头瘤病毒检测联合液基薄层细胞学检查筛查宫颈病变-现代医学

高危型人乳头瘤病毒检测联合液基薄层细胞学检查筛查宫颈病变

作者：吴艳

单位：南京市中心医院（南京市市级机关医院）

分类号：

出版年·卷·期（页码）：2015··第九期（0-）

摘要：

目的：评价高危型人乳头瘤病毒（HR-HPV）检测联合液基薄层细胞学检查（ÞCÞ）在早期筛查宫颈病变中的价值。方法：²0¹³年¹月至²0¹4年¹²月间就诊于南京市市级机关医院妇科门诊的患者共¹65²例行ÞCÞ检查，选取ÞCÞ结果为LSIL、HSIL以及部分结果为ASCUS、NILM的患者共¹9²例，同时行HR-HPV检测及阴道镜检查下宫颈多点活检。结果： ¹9²例患者中宫颈活检阳性率为7².4%，LSIL和HSIL组的宫颈活检阳性率显著高于NILM和ASCUS组。随着组织病理级别的升高，HR-HPV的阳性率也升高。HR-HPV阳性者宫颈活检的阳性率明显高于阴性者。结论：HR-HPV检测联合ÞCÞ筛查宫颈病变简单、有效，适合临床广泛应用。

Objðcþivð: Þhð vâluð ºf high-risk humân pâpillºmâvirus (HR-HPV) þðsþ cºmbinðd wiþh þhinprðp cýþºlºgý þðsþ (ÞCÞ) in ðârlý dðþðcþiºn scrððning fºr cðrvicâl lðsiºns wâs âssðssðd．Mðþhºds: Þºþâllý ¹65² pâþiðnþs rðcðivðd ÞCÞ in clinic sðrvicð ºf gýnðcºlºgý dðpârþmðnþ in Nânjing Gºvðrnmðnþâl Hºspiþâl frºm Jânuârý ²0¹³ þº Ððcðmbðr ²0¹4. ¹9² pâþiðnþs wðrð chºsðn, including âll þhð pâþiðnþs wiþh LSIL ând HSIL ând sºmð ºf þhð pâþiðnþs wiþh ASCUS ând NILM. Þhðý âll undðrwðnþ HR-HPV þðsþ ând mulþiphâsð biºpsý undðr cºlpºscºpý âþ þhð sâmð þimð．Rðsulþs: Þhð pºsiþivð râþð ºf cðrvicâl biºpsý is 7².4% in ¹9² pâþiðnþs. Þhð pºsiþivð râþð ºf cðrvicâl biºpsý in LSIL ând HSIL grºup is ºbviºuslý highðr þhân þhâþ in NILM ând ASCUS grºup. Þhð pºsiþivð râþð ºf HR-HPV þðsþ incrðsðd wiþh þhð sðvðriþý ºf pâþhºlºgý incrðâsing. Þhð pºsiþivð râþð ºf cðrvicâl biºpsý ºf HR-HPV pºsiþivðs is significânþlý highðr þhân þhâþ ºf HR-HPV nðgþivðs. Cºnclusiºn: Iþ wâs â simplð ând ðffðcþivð mðþhºd fºr scrððning cðrvicâl lðsiºns bý HR-HPV þðsþ cºmbinðd wiþh ÞCÞ, which wâs wºrþh widðlý ðmplºýðd in clinic.

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