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老年人心周脂肪组织含量与代谢危险因素及冠心病的相关性
作者:刘艳  
单位:长庆兴隆园医院
关键词:心周脂肪 冠状动脉硬化 体层摄影术 x线计算机 
分类号:
出版年·卷·期(页码):2015·43·第三期(314-317)
摘要:

目的 探讨老年人心周脂肪含量与代谢危险因素及冠心病之间的关系。方法 选取因胸痛住院并例行CT检查的老年患者及有完整健康档案的体检者共483例,其中223人行冠状动脉CT血管造影,测定心包脂肪含量、冠状动脉钙化积分,根据冠状动脉直径狭窄≥50%或达到临床诊断标准将患者分为冠心病组273例和非冠心病组210例;再根据代谢危险因素的数量比较各组间心包脂肪含量。结果 与非冠心病组比较,冠心病组患者心包组织含量差异无统计学意义[(190.9±69.24)cm3 VS(185.72士53.01)cm3, P>0.05]。随代谢危险因素数目的增加,心包脂肪含量虽有上升趋势,但差异无统计学意义(P>0.05)。结论 对于年龄大于60岁以上的老年患者,不能单纯以计算心包脂肪含量来提示冠心病风险,而应综合患者年龄、合并代谢危险因素的数目及药物治疗史来综合评估。

0bjective:To explore the relationship between volume of PAT and coronary artery atherosclerosis and metabolic risk factors in more than sixty years old patients.Methods:483 olders of more than sixty years who underwent 64 slice CT were studied.They were in-patient or have healthy check-up files. 223 patients who underwent Cardiac multislice computed tomography.Multislice computed tomography was used to measure PAT volume and coronary artery calcium score. Patients were divided into coronary artery disease(CAD)and non-CAD group based on the presence of≥50% stenosis or reached clinical diagnosis standard. The patients were grouped according to the number of metabolic risk factors,then PAT volume was compared among the groups.Results:PAT volume was not significantly higher in patients with CAD than that in non-CAD subjects[(190.9±69.24)cm3 vs(185.72士53.01)cm3,P>0.05].As the number of metabolic risk factors increased,the volume of PAT increased correspondingly,but not significant difference among the groups(P>0.05).Conclusion:For more than sixty years olders,MDCT measurement of pericardial adipose tissue volume can not be applied as one of the indicators of coronary artery disease.

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