彩色多普勒超声联合血清附睾蛋白4与糖类抗原¹²5检测对卵巢癌诊断价值的初步探讨-现代医学

彩色多普勒超声联合血清附睾蛋白4与糖类抗原¹²5检测对卵巢癌诊断价值的初步探讨

单位：湖北医药学院附属医院

分类号：

出版年·卷·期（页码）：2015·34·第二期（183-186）

摘要：

目的探讨彩色多普勒超声联合检测血清蛋白HE4、CA125在临床上诊断卵巢癌中的应用价值。方法采用酶联免疫吸附法检测86例卵巢癌患者术前血清蛋白HE4与CA125的水平，结合卵巢癌患者的临床特点与彩超检查结果，并与手术结果及临床病理诊断做对照分析。结果彩超诊断的准确率为87.2%，HE4与CA125诊断的准确率分别为72.1%与75.6%；三者联合诊断的准确率可达97.7%。结论术前采用多普勒超声联合检查血清蛋白HE4与CA125可以有效提高早期卵巢癌诊断的准确性，为患者的早期治疗提供可供可靠的依据。

Objective To investigate the clinical value of color Doppler ultrasound combined with serum HE4 and CA125 detection in ovarian cancer diagnosis. Methods 86 cases of the clinical characteristics of ovarian tumores, the examination by color Doppler ultrasound, and serum HE4 and CA125 levels detected by enzyme-linked immunosorbent assay (ELISA) before their opertion were performed and compared with the results of pathological diagnosis and surgical controls. Results The accuracy rate detected by color Doppler ultrasound was 87.2%; and the accuracy rate detected by serum HE4 and CA125 was 72.1% and 75.6%, respectively. A higher accuracy rate, 97.7%, were obtained by diagnoses combined above three examination methods. Conclusion Color Doppler ultrasound examination combined with serum HE4 and CA125 detection contributes to increasing the accuracy rate for early diagnosis of ovarian cancer, which may provide a reliable base for patient’s early treatment.

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