血栓抽吸联合替罗非班内注射对STEMI介入治疗中心肌组织灌注及临床预后的影响-现代医学

血栓抽吸联合替罗非班内注射对STEMI介入治疗中心肌组织灌注及临床预后的影响

作者：黄南清

单位：广东省中山市小榄人民医院

分类号：

出版年·卷·期（页码）：2014·42·第十期（1172-1176）

摘要：

摘要：目的：研究血栓抽吸联合替罗非班内注射对STEMI介入治疗中心肌组织灌注及临床预后的影响。方法：将ST段抬高型心肌梗死患者120例纳入研究对象，给予介入治疗，随机分为给予血栓抽吸联合替罗非班内注射治疗的观察组和给予常规治疗的对照组，检测术中心肌酶谱指标和术后心功能指标。结果：观察组TIMI、MBG（2.42±0.34、2.36±0.45）、E峰值（75.22±8.39）cm/s、E/A比值(1.412±0.165)、左心室舒张末期直径LVEDD(56.39±5.98)mm、射血分数LVEF（67.38±7.25）%均明显高于对照组；AST、LDH 、CK、CK-MB（28.1±4.5、154.6±34.5、139.5±28.、18.4±3.3）U/L、hs-cTnT（7.9±1.0）ng/L、不良心血管事件（5%）均明显低于对照组（P<0.05）。结论：血栓抽吸联合替罗非班内注射有助于改善术中心肌组织灌注和术后心功能，具有积极的临床应用价值。

Abstract: Objective: To study the effect of thrombus aspiration combined with tirofiban on muscle tissue perfusion and clinical prognosis of STEMI patients received interventional therapy. Methods: 120 cases STEMI patients received interventional therapy were enrolled and randomly divided into observation group given thrombus aspiration combined with tirofiban and control group given conventional therapy. Then myocardial enzymes and cardiac function index were detected. Results: observation group TIMI, MBG (2.42±0.34, 2.36± 0.45) ,E peak (75.22±8.39) cm/s ,E/A ratio (1.412 ±0.165), LVEDD (56.39±5.98) mm, LVEF (67.38±7.25) % were significantly higher than control group . AST, LDH, CK, CK - MB (28.1 ±4.5, 154.6 ±34.5 ,34.5 ±28, 18.4±3.3) U/L, hs - cTnT (7.92±1.01) ng/L, adverse cardiovascular events (5%) were significantly lower than that control group (P < 0.05). Conclusion: thrombus aspiration combined with tirofiban have positive clinical value for it can improve myocardialtissue perfusion and heart function

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