网站首页期刊介绍通知公告编 委 会投稿须知电子期刊广告合作联系我们
最新消息:
替罗非班联合血栓抽吸对急诊PCI患者的近期疗效观察
作者:赵玉勤 何家富 李彬  
单位:湖北襄阳市中心医院
关键词:ST段抬高型急性心肌梗死 急诊经皮冠状动脉介入治疗 替罗非班 血栓抽吸 
分类号:
出版年·卷·期(页码):2014·42·第九期(1007-1010)
摘要:

目的:观察替罗非班联合血栓抽吸对急性ST段抬高型心肌梗死(STEMI)行急诊PCI患者的近期疗效。方法:选取行急诊PCI术的STEMI患者68例,梗死相关血管(IRA)血流TIMI 0-1级。其中37例行替罗非班联合血栓抽吸(血栓抽吸组),另外31例经传统方法完成PCI术(传统PCI组)。比较两组患者IRA的TIMI 血流分级、无复流/慢血流发生率、术中、术后并发症及术后30天内主要心脏不良事件(MACE)发生率。结果:与传统PCI组相比,血栓抽吸组再灌注心律失常、出血、血肿等术中及术后并发症并没有减少(P>0.05)。但血栓抽吸组IRA术后TIMI3血流分级明显高于传统PCI组(P˂0.05),无复流/慢血流发生率、球囊使用例数及术后30天部分MACE发生率显著低于传统PCI组(P˂0.05)。结论:替罗非班联合血栓抽吸能够改善STEMI患者急诊PCI术后IRA血流,降低无复流/慢血流现象及近期MACE的发生率,显著改善STEMI患者的近期预后。

Objective: To study the term effect of tirofiban and thrombus aspiration on emergency percutaneous coronary intervention(PCI) patients with acute ST-segment elevation myocardial infarction(STEMI). Methods: Sixty-eight patients with STEMI received emergency PCI were selected. All the infarct-related coronary artery(IRA) were sub-total or total occlusion and rich in thrombus. Thirty-seven patients received tirofiban and thrombus aspiration(Thrombus Aspiration Group). Other thirty-one patients received routine PCI (Conventional PCI Group).TIMI3 blood flow, no reflow or slow flow incidence of IRA after PCI, intraoperative and postoperative complications and major cardiac adverse event(MACE) in the 30th days of the two groups were compared. Results: Compared with the conventional PCI group, intraoperative and postoperative complications(such as reperfusion arrhythmias, bleeding, hematoma, etc.) in the thrombus aspiration group didn’t reduce(P>0.05). But the thrombus-aspiration group had a significantly higher rate of IRA TIMI3 blood flow, lower rate of no-reflow or slow-flow and lower rate of using balloon(P˂0.05). In addition, MACE occurrence in thrombus-aspiration group was lower partly than conventional PCI group in the 30th days(P˂0.05). Conclusion: Tirofiban and thrombus aspiration can improve IRA bloodstream and reduce no-reflow/slow-flow phenomenon in STEMI patients after emergency PCI, also can decrease MACE occurrence in the 30th days and significantly improve the prognosis of patients with STEMI.

参考文献:
服务与反馈:
文章下载】【发表评论】【查看评论】【加入收藏
提示:您还未登录,请登录!点此登录
您是第 729948 位访问者


 ©《现代医学》编辑部
联系电话:025-83272481;83272479
电子邮件: xdyx@pub.seu.edu.cn

苏ICP备09058541