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原发性膀胱印戒细胞癌的诊断与治疗(附一例报道)
作者:陈绪龙 王海平 赵亚昆  
单位:黑龙江省哈尔滨市哈尔滨医科大学附属第二医院
关键词:膀胱肿瘤 印戒细胞癌 原发性 诊断 治疗 
分类号:
出版年·卷·期(页码):2014·33·第六期(641-644)
摘要:

[摘要] 目的:提高对原发性膀胱印戒细胞癌(Primary Signet-ring cell Carcinoma of the Bladder,PBSRCC)的认知与诊治水平。方法:结合文献回顾性分析我院收治的1例原发性膀胱印戒细胞癌患者的临床资料,就其发病机制、病理特点、临床表现、诊断治疗进行讨论与分析。结果:本例患者为63岁老年男性,因间断性全程无痛肉眼血尿就诊,CTU检查提示膀胱右后壁占位性病变,术前完善相关检查,未见膀胱外病灶,排除转移性肿瘤的可能,行根治性膀胱全切术及双侧输尿管腹壁造口术治疗,术后病理诊断为膀胱印戒细胞癌,转入肿瘤科放化疗治疗,目前正在随访中。结论:原发性膀胱印戒细胞癌是一种罕见的恶性肿瘤,进展快、恶性程度高,局部浸润性生长,有早期扩散转移倾向,预后差。影像学检查及膀胱镜检的综合应用是诊断原发性膀胱印戒细胞癌的主要方法,但其确诊主要依靠病理组织学检查。根治性膀胱全切术是目前首选的治疗方法。

【Abstract】objective:To improve the recognition,diagnosis and treatment of primary signet-ring cell carcinoma of urinary bladder.Methods:A case for primary Signet—ring cell carcinoma of urinary bladder was reported with review of literature. Its pathogenesis, pathology, clinical presentation, diagnosis and treatment for discussion and analysis. Results :The patient was male,aged 63 years,whose chief complain was totally gross hematuria. CTU show a sharp-demarcated tumor in the right rear of the bladder. We could not find any lesions out of the urinary bIadder from pre—operative examinations,and cystectomy plus urter-abdomen ostomy had been operated. The diagnosis of primary SRCC of the case was made by pathological examination after the operation. The patient had been transferred to the department of oncology for futher chemotherapy after operation and now is under follow up.Conclusions:Signet—ring cell carcinoma of urinary bladder has a series of characteristics such as extremely rare occurrence,fast development,highly malignant,local invasive growth,the trend of early pervasion and transfer,and poor prognosis.Iconography and Cystoscopy are the main methods to diagnose Signet—ring cell carcinoma of urinary bladder, Histopathologic examination is the main way to confirm Signet—ring cell carcinoma of urinary bladder.Ridical cystectomy is the best treatment of choice.

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