Objective: To investigate FSWs high-risk behaviors and syphilis, HIV infection among different class places.in order to provide evidence for intervention measures to different grades places. Method: the FSWs in low(below 50 yuan / time), middle (50 ~ 100 yuan / time),high (> 100 yuan / time) place in Liucheng county between January,2009 and December,2012 were selected , according to distribution map for stratified cluster sampling (the number of CSWS ≤20) or random drawing (the number of CSWs in >20), the FSWs were interviewed and examined for HIV antibody and syphilis antibody. Result: there were 1081 FSWs monitored from 2009 to 2012 , most concentrated in low, middle place, most was junior middle school and senior high school ,the FSWs above senior high school were mainly distributed in high places.unmarried and cohabitation FSWs were in middle place ;aredivorced FSWS concentrated were in low places(P<0.05); the FSWs who had worked more than 1 years were most in middle place.the FSWs working time < 6 months were mainly concentrated in low places (P<0.05); " the condom use rate in recent last sexual behaviour” increased with place grade rising, in recent months the rate of never using or sometimes using declined by place grade rising. but the rate of using each time increased by place grade rising(P<0.05); the positive rate of syphilis antibody was higher than that of mid, high place(P<0.05);but the difference of positive rate of HIV antibody was not obvious (P>0.05). Conclusion: according to the demographic characteristics of different grades of FSWs targeted measures were developed, it can help FSWs to more understand the harmfulness of high risk behaviors and then change high risk behavior.