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垂体后叶素用于宫颈冷刀锥切术的临床观察
作者:叶春萍 余宁珠  
单位:南京医科大学附属南京市妇幼保健院
关键词:垂体后叶素  宫颈冷刀锥切术  止血方法 
分类号:
出版年·卷·期(页码):2011·39·第五期(540-543)
摘要:

比较宫颈冷刀锥切术中运用单纯压迫、电凝、注射垂体后叶素三种方法的止血效果。方法:选取自2009年1月1日至2010年12月31日期间入住我院行宫颈冷刀锥切术患者84例。根据初始创面止血方法将患者分为三组:宫颈缝合加局部压迫(单纯组,共28例)、宫颈缝合加局部压迫止血联合电凝术(电凝组,共28例)、宫颈缝合加压迫止血联合局部注射垂体后叶素(垂体后叶素组,共28例);,比较三组患者术中出血情况、手术时间、术后并发症等。结果:平均术中出血量垂体后叶组比单纯组及电凝组显著减少(P< 0.05,F=59.72)。而平均手术时间垂体后叶素组比单纯组稍长,但短于电凝组(P< 0.05,F=26.00)。三组患者术后出血、宫颈管狭窄或粘连、术后感染例数无明显统计学差异.结论 :垂体后叶素应用于宫颈冷刀锥切术中减少了术中出血量,缩短了手术时间,更重要的是不增加术后感染与宫颈狭窄、粘连的发生率,宫颈愈合良好,未增加手术风险,较电凝法更优越,值得推广。

ABSTRACT: OBJECTIVE: To assess the effect of three hemostasis applied in coldknifeconization(CKC) including single compression, electric coagulation and injecting Pituitrin. METHODS: From January 2009 to December 2010, 84 consecutive patients with CIN undergoing coldknifeconization was reviewed retrospectively in order to compare blood lose during operation , time length of operation and postoperative complication of three group(Single compression group, Electric coagulation group, and Injecting Pituitrin group).RESULTS: The mean blood lose of Injecting Pituitrin group is significant less than the other two groups(P< 0.05,F=59.72). The mean operation time length of the Injecting Pituitrin group is longer than Single compression group, but shorter than Electric coagulation group(P< 0.05,F=26.00). The rate of postoperative complication in three groups hadn’t showed significant difference. CONCLUSIONS: The hemostasis of injecting Pituitrin. applied in coldknifeconization reduce blood lose of operation, Shortening time length of operation, and at the same time it did not increase the rate of postoperative complication. It's worth promoting such way of doing it.

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