恶性肿瘤患者化疗后感染的相关因素分析及护理原则-现代医学

恶性肿瘤患者化疗后感染的相关因素分析及护理原则

单位：中国医科大学

分类号：

出版年·卷·期（页码）：2011·39·第三期（355-358）

摘要：

目的探讨恶性肿瘤患者化疗后感染的相关因素分析及护理原则。方法本研究回顾性分析134例恶性肿瘤患者化疗后感染的发生情况及其可能的相关因素，并探讨其护理原则。结果在134例患者中，男性76例，女性58例，年龄36～82岁，中位年龄为59岁，其中非小细胞肺癌46例（34.3%），小细胞肺癌38例（28.4%），胃癌19例（14.2%），结肠癌14例（10.4%），直肠癌8例（6.0%），其它肿瘤9例（6.7%）。单因素Logistic分析结果表明，年龄、侵入性操作、PS评分及并发症发生情况是恶性肿瘤患者发生化疗后感染的重要危险因素。多因素Logistic回归分析结果进一步证实，年龄、侵入性操作及PS评分是恶性肿瘤患者发生化疗后感染的独立危险因素。结论年龄、侵入性操作、PS评分及并发症发生情况是恶性肿瘤患者发生化疗后感染的重要危险因素，应当予以重视并加强对恶性肿瘤化疗后感染患者的护理。

Objective: To investigate related risk factors and nursing principles of in cancer patients with infection after chemotherapy. Methods: Retrospectively analyzed clinical datas of 134 cancer patients with infection after chemotherapy, investigating the incidence, potential risk factors and nursing principles of the infection after chemotherapy. Results: In all 134 cases, 76 male and 58 female patients, the median age is 59 years old (range from 36 to 82). There are 46 non-small cell lung cancer cases (34.3%), 38 small cell lung cancer cases (28.4%), 19 gastric cancer cases (14.2%), 14 colon cancer cases (10.4%), 8 rectal cancer cases (6.0%) and 9 others (6.7%). Univariate logistic regression analysis showed that age, invasive procedures, PS score and complications incidence are risk factors in cancer patients with infection after chemotherapy. Multivariate logistic regression analysis further confirmed that age, invasive procedures, and PS scores are independent risk factors in cancer patients with infection after chemotherapy. Conclusion: Age, invasive procedures, PS score and complications incidence are important risk factors in cancer patients with infection after chemotherapy.

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