2型糖尿病患者血清CA19-9水平分析及影响因素研究-现代医学

2型糖尿病患者血清CA19-9水平分析及影响因素研究

单位：海军总医院特需医疗部

分类号：

出版年·卷·期（页码）：2011·39·第三期（306-308）

摘要：

[摘要]目的：探讨2型糖尿病（T2DM）患者血清CA19-9水平的变化及相关影响因素。方法：选取2型糖尿病患者100例，根据糖化血红蛋白（HbA1C），分为T2DM血糖控制不良组（HbA1C≥7% ,49例）和T2DM血糖控制良好组（HbA1C＜7%,51例）。选取健康体检者50例为对照组；对比分析3组血清CA19-9水平的差异；并对血清CA19-9水平的影响因素进行相关分析。结果：T2DM血糖控制不良组血清CA19-9水平明显高于T2DM血糖控制良好组和对照组（P＜0.05）；T2DM血糖控制良好组血清CA19-9水平明显高于对照组（P＜0.05）。CA19-9水平与HbA1C相关（r=0.3215，P＜0.05）。结论：2型糖尿病患者血清CA19-9水平高于正常人，且与血糖控制水平相关。

[ABSTRACT] Objective: To investigate the serum CA19-9 levels and influencing factors in diabetic patients. Methods: 150 subjects were divided into three groups,ie group of poorly controlled diabetics（HbA1C≥7%）(n=49),group of moderately to well controlled diabetics（HbA1C＜7%）(n=51) and group of healthy control(n=50). Serum CA19-9 level was comparatively analyzed.Pearson analysis was performed to value the relation between CA19-9 and influencing factors.Results: Serum CA19-9 levels was significantly higher in the group of poorly controlled diabetics compared with moderately to well controlled diabetics and control group(P＜0.05).It was also higher in the group of well controlled diabetics than control group(P＜0.05).Pearson analysis showed a positive correlation between CA19-9 and HbA1C(r=0.3215，P＜0.05).Conclusion: Serum CA19-9 concentration was increased in diabetic patients and correlate with the control of blood glucose.

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