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172例宫颈电环与冷刀锥切术对治疗宫颈上皮内瘤变Ⅲ级的
作者:刘庆芝  
单位:深圳市妇幼保健院
关键词:【关键词】 宫颈上皮内瘤变 环形电切术 冷刀锥切术 
分类号:
出版年·卷·期(页码):2011·39·第二期(162-165)
摘要:

【摘要】 目的:研究比较宫颈环形电切术(LEEP)和冷刀宫颈锥切术(CKC)对宫颈上皮内瘤变Ⅲ级(CINⅢ)的临床疗效。方法:将172例经宫颈细胞学筛查、阴道镜检查及阴道镜下多点活检病理检查确诊为CINⅢ患者随机分为两组,观察组行LEEP,对照组行CKC,观察两组手术时间、术中出血量、切口愈合时间及手术前后病理比较。结果:两组手术治疗效果相当,LEEP组手术时间、切口愈合时间明显低于CKC组,术中出血量显著少于CKC组 (P<0.05)。结论:LEEP是目前诊治CINⅢ的安全有效方法,具有手术时间短、术中出血少等优点,患者创伤小、痛苦少,优于CKC,值得进一步深入地研究并加以推广。

Abstract:Objective To compare application values of loop electrosurgical excision procedure(LEEP) and cold knife conization(CKC)for the treatment of cervical intraepithelial neoplasia Ⅲ(CINⅢ).Methods 172 patients with CINⅢ were diagnosed by TCT and multiple punch biopsy under colposcope.They were divided into two groups randomly:93 patients in the LEEP group and 79 patients in CKC group. The operation time, amount of blood loss, time of wound healing and changes of pathological grades in the two groups were studied.Results The two groups had the same values in therapeutic efficacy. LEEP group had shorter operative time and time of wound healing,little amount of blood loss than CKC group,there were significant differences between the two groups (P<0.05).Conclusion LEEP is a safe and efective treating method to CINⅢ,LEEP had the merits of short operative time,little blood loss,invasion and pain,and rapid recovery.LEEP is worth spreading.

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