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液基细胞学联合HPV基因分型检测在宫颈癌前病变筛查中的应用
作者:姜清明 
单位:韶关市第二人民医院检验科
关键词:  [关键词] 液基细胞学 人乳头状瘤病毒 宫颈病变 诊断 
分类号:
出版年·卷·期(页码):2011·39·第一期(45-47)
摘要:

[摘要] 目的:探讨液基细胞学(Thinprep cytologic test,TCT)联合HPV分型检测对宫颈病变的临床诊断价值。方法:我院2009年6月~2009年12月TCT检查ASCUS及以上的患者340例,其中ASCUS266例,LSIL63例,HSIL6例,SCC5例,均进行21种HPV基因亚型检查。结果:HPV检查阳性患者116例,其中高危型患者39例,来自ASCUS、LSIL、HSIL 、SCC患者分别为 16、14 、4 、5例,平均年龄42.1岁,低危型患者77例,来自ASCUS、LSIL、HSIL 、SCC患者分别为 53、22 、2、0例,平均年龄33.5岁。结论:TCT检查与HPV分型检测是筛查宫颈病变的有效方法,两者结合可以早期诊断宫颈病变,对患者的随诊具有指导意义。

[Abstract] Objective: To explore the clinlical diagnosis value of Thinprep cytologic test (TCT) combined various subtype human papillovirus (HPV) infection with cervical lesions. Methods: From June 2009 to December 2009 in our hospital,340 patients underwent TCT examination showedpositive(ASCUS and above),cases of ASCUS,LSIL,HSIL,SCC were266,63,6,5 respectively,all of them received 21 subtype HPV testing.Results: 116 cases with HPV positive,subtype of high risk and low risk were 39 and 77 cases,cases of ASCUS,LSIL,HSIL,SCC were 16,14,4,5 and 53,22 ,2,0,mean age was 42.1 and 33.5 years respectively. Conclusion: Thinprep cytologic test and HPV testing are effective methods for cervical lesions screening,the combination of the two methods can improve the early diagnosis rate of cervical lesions,possessing instructive significance on follow-up of the patients.

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