[Objective]:To evaluate the diagnostic significance by detection rheumatoid factor(RF-IgM) and anti-cyclic citrullinated peptide(CCP) antibody,and their correlation with Disease activity. [ Methods] : we used enzyme-linked immunosorbent assay and rate nephelometry to detect CCP and RF in patients with 65 RA、68 non-RA.[Results]:The sensitivity for RF and anti-CCP were 81.5% and 95.4%,respectively, and the specificity were 58.8%,95.6%, respectively.The specificity was increased by combining the tests.A significant correlation was found between RF、anti-CCP and CRP、ESR, respectively. [Conclusions]:The higher specificity was founded by combining the tests.There was association between RF、anti-CCP and disease activity. |