4例IgD型多发性骨髓瘤临床报道及文献复习-现代医学

4例IgD型多发性骨髓瘤临床报道及文献复习

单位：北京世纪坛医院

分类号：

出版年·卷·期（页码）：2011·39·第一期（51-53）

摘要：

目的：提高对IgD型多发性骨髓瘤的认识及诊疗水平。方法：回顾分析4例IgD型多发性骨髓瘤患者的临床特点并复习相关文献。结果：患者发病平均60.75岁， IgD-κ轻链型1例（25%），IgDλ轻链型3例（75%）。临床分期4例均为ⅢB期。临床表现包括骨痛、贫血、消瘦、浮肿、肾功能不全、恶性胸腔积液等。β2-MG、LDH、CRP不同程度增高。中为生存期31个月。结论：IgD型多发性骨髓瘤临床少见，预后不良，需在诊疗工作中加以注意。

Objectives: To improve the level of recognition, diagnostic and treatment of IgD multiple myeloma (MM). METHODS: Four IgD MM patients were studied retrospectively on clinical characteristics, and related literatures were reviewed. RESULTS: The median incidence of age was 60.75 years. Third of the fourth were lambda-light chain(75%), only one was IgD-kappa light chain type(25%). All the patients had stage IIIB. The presenting features included bone pain, anemia, wasting, renal inadequacy, massive pleural effusion etc. β2-MG、LDH and CRP all elevated in some degree. The median survival time was 31 months. CONCLUSION: IgD MM is rear and has a poor prognosis. We should pay attention during our daily work.

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