黄芪桂枝五物汤对产后痹证患者关节疼痛、睡眠质量的影响-现代医学

黄芪桂枝五物汤对产后痹证患者关节疼痛、睡眠质量的影响

单位：陕西省宝鸡市妇幼保健院产科, 陕西宝鸡 721000

分类号：R741.46;R271.43

出版年·卷·期（页码）：2018·46·第六期（611-615）

摘要：

目的：探讨黄芪桂枝五物汤加减治疗产后痹证患者的临床疗效及对患者关节疼痛、睡眠质量的影响。方法：将82例产后痹证患者随机分为研究组与对照组，各41例。两组均予以西药治疗，研究组在此基础上应用黄芪桂枝五物汤加减治疗，疗程均为30 d。对比两组临床疗效，记录关节疼痛数目、晨僵持续时间，评价治疗前后中医症状积分、疼痛数字评分量表（NRS）评分及匹茨堡睡眠质量指数（PSQI）。结果：研究组总有效率（97.56%）较对照组（85.37%）明显提高（P<0.05）；治疗后研究组的疼痛关节数、晨僵持续时间、中医症状积分、疼痛NRS评分及PSQI评分均显著低于对照组（P<0.05）。结论：黄芪桂枝五物汤加减治疗产后痹证疗效确切，具有改善临床症状、减轻关节疼痛及改善睡眠质量等作用。

Objective:To investigate the clinical effects of Huangqi Guizhi Wuwu decoction in treatment of postpartum arthralgia and its influence on joint pain and sleep quality. Methods:Totally 82 cases of postpartum arthralgia patients were randomly divided into research group and control group,with 41 cases in each group. Both groups were treated with western medicine,on the basis, the research group received Huangqi Guizhi Wuwu decoction addition and subtraction therapy for 30 days.The clinical efficacy was compared between the two groups,the number of joint pain,the duration of morning stiffness were recorded. The scores of traditional Chinese medicinesymptom score, pain numerical rating scale(NRS) and Pittsburgh Sleep Quality Index (PSQI) were evaluated before and after treatment. Results:The total effective rate in research group (97.56%) was significantly higher than that in control group (85.37%) (P<0.05). After treatment, the number of painful joints, duration of morning stiffness, traditional Chinese medicine symptom score, pain NRS score and PSQI score in research group were significantly lower than those in the control group (P<0.05). Conclusion:Huangqi Guizhi Wuwu decoction addition and subtraction is effective in treating postpartum arthralgia,which can improve clinical symptoms, reduce joint pain and improve the sleep quality.

参考文献：

[1] 潘碧琦,邱少红,宋曙霞,等.中药治疗产后身痛的用药规律研究[J].中医药导报,2017,23(13):55-58.
[2] 陈伟.黄芪桂枝五物汤加减治疗产后身痛临床观察[J].中国医药导刊,2014,16(9):1219-1220.
[3] 罗颂平,谈勇.中医妇科学[M].2版.北京:人民卫生出版社,2012:131-135.
[4] 国家中医药管理局.中医病证诊断疗效标准[M].南京:南京大学出版社,1994:46-47.
[5] 路桃影,李艳,夏萍,等.匹兹堡睡眠质量指数的信度及效度分析[J].重庆医学,2014(3):260-263.
[6] 郑筱萸.中药新药临床研究指导原则[M].北京:中国医药科技出版社,2002:292-293.
[7] 辛军,马晓能,李学军,等.逍遥散合黄芪桂枝五物汤治疗肝郁气滞产后痹随机平行对照研究[J].实用中医内科杂志,2014,28(9):14-15.
[8] 王金凤,刘桂兰,王芳芳,等.补肾益气养血通络之膏方对产后身痛疗效的临床研究[J].中医药学报,2015,43(2):69-71.
[9] 殷彩梅.黄芪桂枝五物汤加减治疗产后痹30例疗效观察[J].中国医学装备,2014,11(12):268.
[10] 李楠,林昌松,刘清平,等.产后痹方治疗产后关节痛的疗效评价[J].辽宁中医杂志,2016,14(2):333-335.
[11] 刘成全,顾润环.黄芪桂枝五物汤治疗妇科病验案举隅[J].中医药导报,2016,22(19):103-105.
[12] 张金兰,张金锁,周敏.加味黄芪桂枝五物汤治疗产后身痛疗效观察[J].河北中医药学报,2011,26(2):28.
[13] 陈琼,张婷婷,谭丽,等.产后身痛中医药治疗研究进展[J].辽宁中医药大学学报,2012,14(2):55-57.
[14] 卢余莉.临证治验析产后身痛用药之理[J].湖北中医药大学学报,2014,16(6):64-65.
[15] 石白,王新贤,殷海波,等.运用黄芪桂枝五物汤治疗产后痹的体会[J].国际中医中药杂志,2017,39(7):648-649.
[16] 杜杰.黄芪总苷和人参皂苷降低缺血性脑卒中患者脑脊液中谷氨酸、磷酸化Tau[J].东南大学学报:医学版,2017,36(5):828-832.
[17] 刘亚玮,毕丽鑫,赵磊.黄芪注射液辅助治疗耐多药肺结核的临床效果及对免疫功能的影响[J].现代医学,2016,44(4):462-466.
[18] 岳洁,刘晓华,申英.剖宫产术式对妇女产后痹发生的影响调查及中医调理效果分析[J].辽宁中医杂志,2017,15(3):519-522.

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